This NASA image shows the SpaceX Dragon cargo craft approaches the International Space Station for a docking 424 kilometers above the Atlantic ocean in between South America and Africa on March 16, 2023. (HANDOUT / NASA / AFP)

LOS ANGELES - The SpaceX Dragon cargo resupply spacecraft will depart the International Space Station on Thursday and return scientific research samples and hardware to Earth, the US National Aeronautics and Space Administration said on Monday.

The spacecraft is scheduled undock from the ISS at 12:05 pm Eastern Time Thursday, and make a parachute-assisted splashdown about 2:30 am Friday, off the coast of the southeastern US state of Florida.

Dragon will carry back to Earth over 3,600 pounds of supplies and scientific experiments designed to take advantage of the space station's microgravity environment, according to NASA.

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The spacecraft was launched June 5 on a SpaceX Falcon 9 rocket from NASA's Kennedy Space Center. It arrived at the ISS on June 6, delivering more than 7,000 pounds of research investigations, crew supplies, and station hardware.