KYIV/MOSCOW - Russia launched cruise and ballistic missiles at Ukraine on Wednesday morning in a new massive attack, the Ukrainian Air Force said.

A series of explosions were heard in the eastern city of Kharkiv, while air defense systems were active near the city of Cherkasy in central Ukraine, public broadcaster Suspilne reported.

The missile attack followed overnight drone strikes by Ukraine.  

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Meanwhile, the Ukrainian army carried out its "largest strike" on Russian military targets, 200 to 1,100 kilometers deep into the Russian territory, early Tuesday morning, General Staff of the Armed Forces of Ukraine confirmed on Facebook.

Targets of the strike included oil storage facilities, military plants and other locations in such areas as Bryansk, Saratov, Tula regions and the Republic of Tatarstan, according to a statement.

Russian Defense Ministry confirmed the attack on Tuesday, accusing Ukraine of using US- and British-made long-range missiles and drones.

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The Ukranian actions "supported by Western handlers will trigger retaliation," the ministry said in a statement.

Dozens of drones were shot down overnight across multiple regions in Russia, with damage reported at industrial plants and residential buildings, TASS news agency reported, citing local officials.

No casualties were recorded, it added.